Registration Dossier
Registration Dossier
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EC number: 219-637-2 | CAS number: 2487-90-3
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
No reproductive toxicity studies have been conducted with trimethoxysilane as this is a transported isolated intermediate (Annex VII dossier).
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Effects on developmental toxicity
Description of key information
No developmental toxicity studies have been conducted with trimethoxysilane as this is a transported isolated intermediate (Annex VII dossier).
The substance is a highly reactive toxicant, it is unlikely to reach the reproductive organs or the embryo/fetus and result in toxicity.
Furthermore, reliable measured data are available for the ultimate hydrolysis product, silicic acid, which indicate no hazard for systemic toxicity.
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
