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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Key value determined in experimental study performed to OECD Guideline 202, EU Method C2 and US EPA Procedure OCSPP 850.1010.

Key value for chemical safety assessment

Additional information

Under the conditions of this Daphnia magna acute immobilisation study the calculated and observed endpoints for the effect of CUCURBIT[8]URIL were the followings:

The 24h EC50 value: > 100 % saturated solution (nominal)

The 48h EC50 value: > 100 % saturated solution (nominal)

The 48h EC100 value: > 100 % saturated solution (nominal)

The 48h No-Observed Effect Concentration (NOEC):

> 100 % saturated solution (nominal)

The 48h Lowest Observed Effect Concentration (LOEC):

> 100 % saturated solution (nominal)

Based on the results of this study, the test item CUCURBIT[8]URIL had no toxic effect at saturation [36.02 mg/L Test Item, measured by NPOC (Non-Purgeable Organic Carbon) content]; the EC50 results and the LOEC are higher than the solubility level of the test item in the test medium.