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Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable publication which meets basic scientific principles. Results only as data tables.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1962

Materials and methods

Principles of method if other than guideline:
see details in "Any other information on materials and methods incl. tables"
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dimethylmorpholine
EC Number:
205-509-3
EC Name:
2,6-dimethylmorpholine
Cas Number:
141-91-3
Molecular formula:
C6H13NO
IUPAC Name:
2,6-dimethylmorpholine

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
no data
Observation period (in vivo):
no data
Number of animals or in vitro replicates:
no data

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Time point:
other: 24 h
Score:
7
Max. score:
10
Reversibility:
not specified

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification