Registration Dossier
Registration Dossier
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EC number: 940-742-0 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The conclusions of this endpoint is based on read across from the source substance Humic acids, potassium salts. A justification document for read-across is attached to the dossier.
The toxicokinetic behaviour of Humic acids, potassium salts was estimated on the basis the toxocological tests results.
The systemic effects were described after single oral administration of the substance to rats. The substance is absorbed from digestive system. After skin or eye single application systemic toxic effects were not detected – the test substance does not penetrate through the skin or eye.
Effect on blood parameters and on urine excretion system in 28-day oral study confirmed that the test substance is absorbed from digestive tract, enters the blood circulation and probably is eliminated by kidneys.
Results of reproduction toxicity study showed that the test substance is absorbed from the digestive tract and enters the reproductive system of males and females - influence on sperm quality and early intrauterine development of offspring.
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