Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-512-3 | CAS number: 823-36-9
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- QSAR Toolbox 3.1.0.21
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- VegaNIC - Vega Non - Interactive Client - version 1.0.8
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- T.E.S.T. version 4.1
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- ChemProp - QSAR 6 Public OSIRIS Edition
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-ethylcyclopentane-1,3-dione
- EC Number:
- 212-512-3
- EC Name:
- 2-ethylcyclopentane-1,3-dione
- Cas Number:
- 823-36-9
- Molecular formula:
- C7H10O2
- IUPAC Name:
- 2-ethylcyclopentane-1,3-dione
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 740.03 mg/L
- Nominal / measured:
- estimated
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Software Database / Method Endpoint Test duration Species Predicted value QSAR Toolbox Aquatic OASIS LC50 96 h Pimephales promales 279 mg/l VegaNIC N.A. LC50 96 h Fathead minnow 178.94 mg/l VegaNIC N.A. Alerts - - NON Toxic T.E.S.T. FDA Method LC50 96 h Fathead minnow 595.93 mg/l T.E.S.T. Nearest neighbor method LC50 96 h Fathead minnow 1325,22 mg/l ChemProp Van Leeuwen et al model LC50 96 h Fathead minnow 1321.06 mg/l
Applicant's summary and conclusion
- Conclusions:
- According to (Q)SAR modells: QSAR Toolbox, VegaNIC, T.E.S.T., ChemProp the predicted values indicated that Ethyl-cyclopentanedione is not hazardous to fish. The result does not meet the requirement of any Aquatic Acute Category.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
