Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: detailed report not available: information about purity of the substance missing; sex, origin and strain, bodyweight and age of the animals missing; no clear description of doses administered; detailed results missing
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1977
Report date:
1977

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
not avaialable
GLP compliance:
not specified
Test type:
other: no information available
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6,6-trimethylcyclohex-2-ene-1,4-dione
EC Number:
214-406-2
EC Name:
2,6,6-trimethylcyclohex-2-ene-1,4-dione
Cas Number:
1125-21-9
Molecular formula:
C9H12O2
IUPAC Name:
2,6,6-trimethylcyclohex-2-ene-1,4-dione

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
unchanged (no vehicle)
Doses:
no information
No. of animals per sex per dose:
5 -10
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 1 410 mg/kg bw
Based on:
test mat.
95% CL:
>= 1 250 - <= 1 570

Any other information on results incl. tables

-

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Conclusions:
Substance should be classified as harmful
Executive summary:

-