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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1972
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: only orientating information about the inhalation hazard. Poorly characterized test atmosphere.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1972
Report date:
1972

Materials and methods

Principles of method if other than guideline:
Whole body exposure to dust generated by blowing air through a layer of the test substance.
GLP compliance:
no
Test type:
other: inhalation hazard test

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydrogen [tris[[[3-[(2-ethylhexyl)oxy]propyl]amino]sulphonyl]-29H,31H-phthalocyaninesulphonato(3-)-N29,N30,N31,N32]cuprate(1-), compound with 3-[(2-ethylhexyl)oxy]propylamine (1:1)
EC Number:
304-661-9
EC Name:
Hydrogen [tris[[[3-[(2-ethylhexyl)oxy]propyl]amino]sulphonyl]-29H,31H-phthalocyaninesulphonato(3-)-N29,N30,N31,N32]cuprate(1-), compound with 3-[(2-ethylhexyl)oxy]propylamine (1:1)
Cas Number:
94277-77-7
Molecular formula:
C65 H84 Cu N11 O12 S4 .C11 H25 N O .H
IUPAC Name:
hydrogen [tris[[[3-[(2-ethylhexyl)oxy]propyl]amino]sulphonyl]-29H,31H-phthalocyaninesulphonato(3-)-N29,N30,N31,N32]cuprate(1-), compound with 3-[(2-ethylhexyl)oxy]propylamine (1:1)
Details on test material:
Name in report: Cu-Phthalocyanin-sulfochlorid, umgesetzt mit 2-2-Aethylhexoxypropylamin
Substance type: solid, blue

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: dust
Analytical verification of test atmosphere concentrations:
no
Duration of exposure:
ca. 8
Concentrations:
Mean concentration: 8.29 mg/l
No. of animals per sex per dose:
12
Control animals:
yes
Details on study design:
Whole body exposure to dust generated by blowing air through a layer of the test substance.
Temperature 20°C
Air flow: 200L per hour
Strong dust generation observed.

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LC0
Effect level:
>= 8.29 mg/L air
Based on:
test mat.
Exp. duration:
8 h
Remarks on result:
other: Concentration determined by weight difference of test substance layer at the beginning and at the end of the exposure period.
Mortality:
None
Clinical signs:
other: Slight mucosal irritations; fur intense blue-coloured
Gross pathology:
Sacrificed animals: organs: nothing abnormal detected

Applicant's summary and conclusion

Interpretation of results:
relatively harmless
Remarks:
Migrated information

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