Registration Dossier
Registration Dossier
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EC number: 304-661-9 | CAS number: 94277-77-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1972
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only orientating information about the inhalation hazard. Poorly characterized test atmosphere.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 972
- Report date:
- 1972
Materials and methods
- Principles of method if other than guideline:
- Whole body exposure to dust generated by blowing air through a layer of the test substance.
- GLP compliance:
- no
- Test type:
- other: inhalation hazard test
Test material
- Reference substance name:
- Hydrogen [tris[[[3-[(2-ethylhexyl)oxy]propyl]amino]sulphonyl]-29H,31H-phthalocyaninesulphonato(3-)-N29,N30,N31,N32]cuprate(1-), compound with 3-[(2-ethylhexyl)oxy]propylamine (1:1)
- EC Number:
- 304-661-9
- EC Name:
- Hydrogen [tris[[[3-[(2-ethylhexyl)oxy]propyl]amino]sulphonyl]-29H,31H-phthalocyaninesulphonato(3-)-N29,N30,N31,N32]cuprate(1-), compound with 3-[(2-ethylhexyl)oxy]propylamine (1:1)
- Cas Number:
- 94277-77-7
- Molecular formula:
- C65 H84 Cu N11 O12 S4 .C11 H25 N O .H
- IUPAC Name:
- copper(2+) hydrogen 3-[(2-ethylhexyl)oxy]propan-1-amine 14,24,32-tris({[({3-[(2-ethylhexyl)oxy]propyl}amino)oxy]sulfonyl})-2,11,20,29,37,38,39,40-octaazanonacyclo[28.6.1.1³,¹⁰.1¹²,¹⁹.1²¹,²⁸.0⁴,⁹.0¹³,¹⁸.0²²,²⁷.0³¹,³⁶]tetraconta-1,3(40),4,6,8,10,12,14,16,18,20,22,24,26,28(38),29,31,33,35-nonadecaene-37,39-diide-5-sulfonate
- Details on test material:
- Name in report: Cu-Phthalocyanin-sulfochlorid, umgesetzt mit 2-2-Aethylhexoxypropylamin
Substance type: solid, blue
Constituent 1
Test animals
- Species:
- rat
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: dust
- Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- ca. 8
- Concentrations:
- Mean concentration: 8.29 mg/l
- No. of animals per sex per dose:
- 12
- Control animals:
- yes
- Details on study design:
- Whole body exposure to dust generated by blowing air through a layer of the test substance.
Temperature 20°C
Air flow: 200L per hour
Strong dust generation observed.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC0
- Effect level:
- >= 8.29 mg/L air
- Based on:
- test mat.
- Exp. duration:
- 8 h
- Remarks on result:
- other: Concentration determined by weight difference of test substance layer at the beginning and at the end of the exposure period.
- Mortality:
- None
- Clinical signs:
- other: Slight mucosal irritations; fur intense blue-coloured
- Gross pathology:
- Sacrificed animals: organs: nothing abnormal detected
Applicant's summary and conclusion
- Interpretation of results:
- relatively harmless
- Remarks:
- Migrated information
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