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Administrative data

Endpoint:
auto-flammability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02 June 2015-18 August 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-compliant study in accordance with UN-MTC Section 33.3.1.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: UN ST/SG/AC.10/11/Rev.5: Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part III Section 33.3.1 "Substances liable to spontaneous combustion” (2009).
Deviations:
no
Principles of method if other than guideline:
UN MTC Section 33.3.1.4 - Test N.4: Test method for self-heating substances (2009)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID
EC Number:
608-945-6
Cas Number:
340-90-9
Molecular formula:
C13H11NO6
IUPAC Name:
(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name (as cited in study report): Phthalyl-L-Glu
- Appearance: white powder
- Storage conditions: room temperature

Results and discussion

Auto-ignition temperature (liquids / gases)
Remarks on result:
other: A negative result was obtained in the test using a 10 cm sample cube at 140°C: no spontaneous ignition occurred and no exothermic effect was observed.
Relative self-ignition temperature (solids)
Remarks on result:
other: A negative result was obtained in the test using a 10 cm sample cube at 140°C: no spontaneous ignition occurred and no exothermic effect was observed.

Any other information on results incl. tables

Visual observation of the test sample after the experiment: the test substance had turned into a white residue with some dark discolouration. It indicated that the test substance had slightly decomposed and/or reacted during the experiment. 

 

 

Applicant's summary and conclusion

Conclusions:
In a GLP-compliant study performed in accordance with UN-MTC Section 33.3.1 (Test N.4), a negative result was obtained using a 10 cm sample cube at 140°C. From this it was concluded that Phthalyl-L-Glu is not a self-heating substance.