Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
explosive properties of explosives
Study period:
02 June 2015-18 August 2015
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Justification for type of information:
Expert Statement

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: UN ST/SG/AC.10/11/Rev.5: Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Appendix 6 "Screening procedures" (2009)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.14 (Explosive properties)
Version / remarks:
(2008)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID
EC Number:
608-945-6
Cas Number:
340-90-9
Molecular formula:
C13H11NO6
IUPAC Name:
(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID
Details on test material:
- No test material; a statement has been written.
- Name of the substance (as cited in study report): Phthalyl-L-Glu

Results and discussion

Any other information on results incl. tables

A substance is considered explosive when it can react to produce very rapid increases in temperature or pressure.

 

The test substance does not contain chemical groups which are associated with explosive properties. The molecular structures of impurities at ≤ 1% were not taken into account.

 

In conclusion, Phthalyl-L-Glu has no explosive properties.

Applicant's summary and conclusion

Conclusions:
From a GLP-compliant statement based on structural features, it was concluded that Phthalyl-L-Glu has no explosive properties.