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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07/09/2015-08/09/2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental result perfromed using standard method of estimation
Qualifier:
according to guideline
Guideline:
other: As mention below
Principles of method if other than guideline:
The particle size distribution of test substance Denatonium Benzoate (CAS No. 3734-33-6) was determined by granulometric analysis with rotap sieve shaker
GLP compliance:
no
Type of method:
sieving
Type of particle tested:
primary particle
Type of distribution:
counted distribution
Specific details on test material used for the study:
- Name of test material (as cited in study report): Denatonium benzoate
- IUPAC NAme : benzyl({[(2,6-dimethylphenyl)carbamoyl]methyl})diethylazanium benzoate hydrate
- Molecular formula: C21H29N2O.C7H5O2
- Molecular weight: 446.58 g/mol
- Smiles : CC[N+](CC)(Cc1ccccc1)CC(=O)Nc2c(cccc2C)C.c1ccc(cc1)C(=O)[O-]
- InChI : 1S/C21H28N2O.C7H6O2/c1-5-23(6-2,15-19-13-8-7-9-14-19)16-20(24)22-21-17(3)11-10-12-18(21)4;8-7(9)6-4-2-1-3-5-6/h7-14H,5-6,15- 16H2,1-4H3;1-5H,(H,8,9)
- Substance type: organic
- Physical state: Solid
Key result
Percentile:
D50
Mean:
>= 150 µm
Remarks on result:
other: Mass median diameter
No.:
#1
Size:
>= 150 µm
Distribution:
>= 99 %

OBSERVATION TABLE:

Amount of sample weighed (g) =10 gm

Method run time (minutes) =10 min

Weight of empty container (g) =0.261 g

 Sieve sizes(in microns)  Weight of container + test substance (g)  Sample quantity retained after sieving (g)  Percentage (%) of sample*
 150 microns  10.261  9.908  99.08%
Conclusions:
The particle size distribution of test substance Denatonium Benzoate (CAS No. 3734-33-6) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to be in the range of 150 micron.
Executive summary:

The particle size distribution of test substance Denatonium Benzoate (CAS No. 3734-33-6) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution of over 99% particles was determine to be in the range of 150 micron.

Description of key information

The particle size distribution of test substance Denatonium Benzoate (CAS No. 3734-33-6) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution of over 99% particles was determine to be in the range of 150 micron.

Additional information

The particle size distribution of test substance Denatonium Benzoate (CAS No. 3734-33-6) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution of over 99% particles was determine to be in the range of 150 micron.