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EC number: 210-276-6 | CAS number: 611-71-2
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06-05-2002 to 21-05-2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study (OECD), validity criteria fulfilled
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- L-2-hydroxy-2-phenylacetic acid
- EC Number:
- 210-276-6
- EC Name:
- L-2-hydroxy-2-phenylacetic acid
- Cas Number:
- 611-71-2
- Molecular formula:
- C8H8O3
- IUPAC Name:
- hydroxy(phenyl)acetic acid
- Details on test material:
- ChiPros (R)-Mandelsäure: (R)-mandelic acid (purity: 100 %)
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 14 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Initial conc.:
- 32 mg/L
- Based on:
- test mat.
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Value:
- ca. 90 - ca. 100
- Sampling time:
- 14 d
- Details on results:
- RS-Freetext:
DOC (mg/l, average values):
time BC RS IH PC AC TS
(d)
0 0.3 20.0 41.3 21.5 21.6 21.4
1 0.3 20.6 41.5 21.4 22.0 21.4
3 1.9 18.2 20.3 21.7 22.2 2.4
5 0.5 2.1 2.9 21.3 21.9 1.2
7 1.6 2.6 3.0 21.9 1.5
10 0.8 2.5 2.9 21.6 1.1
13 1.1 2.6 2.4 22.0 1.1
14 0.8 2.2 2.0 22.0 1.2
DOC decrease (%):
time RS IH PC AC TS
(d)
0 0 0 0 0 0
1 -3 0 0 -1 -2
3 17 55 -1 5 100
5 92 94 1 0 97
7 95 97 -2 100
10 91 95 0 99
13 92 97 -2 100
14 93 97 -2 99
BC = blank control
RS = reference substance
IH = inhibition control
PC = abiotic control
AC = adsorption control
TS = test substance
- adaptation phase: 1-2 days
- degradation phase: 1-2 days
- 10-day window met: yes
Kinetic of test substance (in %):
< 0 after 1 day(s)
ca. 100 after 3 day(s)
ca. 100 after 7 day(s)
ca. 99 after 14 day(s)
Kinetic of control substance (in %):
ca. 90 ... 100 after 14 day(s)
Degradation products: not measured
Any other information on results incl. tables
preliminary investigations (non-GLP):
- TOC = 627 mg/g
- DOC = 634 mg/g
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
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