Registration Dossier
Registration Dossier
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EC number: 811-484-5 | CAS number: 680972-33-2
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in mammalian cells
- Remarks:
- Test is on going
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 476 (In Vitro Mammalian Cell Gene Mutation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Type of assay:
- in vitro mammalian cell gene mutation test using the Hprt and xprt genes
Test material
- Reference substance name:
- Sodium p-cumenesulphonate
- EC Number:
- 239-854-6
- EC Name:
- Sodium p-cumenesulphonate
- Cas Number:
- 15763-76-5
- Molecular formula:
- C9H12O3S.Na
- IUPAC Name:
- sodium 4-isopropylbenzenesulfonate
- Details on test material:
- Purity: 40.2 % (aqueous solution)
Constituent 1
Method
- Metabolic activation:
- with and without
Controls
- Untreated negative controls:
- yes
- Negative solvent / vehicle controls:
- yes
- True negative controls:
- yes
- Positive controls:
- yes
- Remarks:
- Test on going
Results and discussion
- Remarks on result:
- other: Test on going
Applicant's summary and conclusion
- Conclusions:
- The test is on going on the sodium salt and is expetced to be negative.
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