2,4-dichloroaniline

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Type of information:

other: applicant's summary entry

Adequacy of study:

other information

Reliability:

other: applicant's summary entry

Rationale for reliability incl. deficiencies:

other: No reliability is given as this is an applicant's summary entry for a variety of studies.

Data source

Reference

Reference 1

Reference Type:

secondary source

Title:

2,4-Dichloranilin; 2,5-Dichloranilin; 3,4-Dichloranilin

Author:

Beratergremium für umweltrelevante Altstoffe (BUA)

Year:

1994

Bibliographic source:

Wissenschaftliche Verlagsgesellschaft, BUA report 140

Reference 2

Reference Type:

publication

Title:

Fate and effects of 3,4-dichloroaniline in the laboratory and in outdoor ponds: I Fate.

Author:

Wolff C. J. M. and Crosslander N. O.

Year:

1985

Bibliographic source:

Environ. Toxicol. Chem. 4, 481-487

Reference 3

Reference Type:

publication

Title:

Predicting the hazards of chemicals to aquatic environments.

Author:

Crossland N. O.

Year:

1986

Bibliographic source:

Chem. Ind. 21, 740-744

Materials and methods

Principles of method if other than guideline:

applicant's summary entry

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2,4-dichloroaniline

EC Number:

209-057-8

EC Name:

2,4-dichloroaniline

Cas Number:

554-00-7

Molecular formula:

C6H5Cl2N

IUPAC Name:

2,4-dichloroaniline

Results and discussion

Any other information on results incl. tables

reliable studies (rel. 1 + 2)

Wolff and Crosslander, 1985

On the basis of logical considerations Wolff and Crosslander make the following prediction for all three dichloroanilines: "Hydrolysis is not expected to occur since the covalent bond of a substituent attached to an aromatic ring is resistant to this process because of the high negative charge-density of the aromatic nucleus."

 

 

unreliable source (rel. 3 + 4)

 

Crossland, 1986

From the physical and chemical properties of dichloroaniline and taking into consideration relevant environmental parameters (depth of water and sediment, temperature, pH, windspeed at water surface), we were able to conclude that hydrolysis would be an unimportant loss process from freshwater ponds. This publication is considered not to be valid due to insufficient documentation.

 

BUA report, 1994

The German BUA report which cites Wolff and Crosslander (1985) says: "2,4-dichloroaniline is not expected to undergo significant elimination by hydrolysis under environmental conditions."