Registration Dossier
Registration Dossier
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EC number: 235-008-5 | CAS number: 12054-48-7
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable well documented publications
Data source
Reference
- Reference Type:
- publication
- Title:
- Lethal effects of zinc and nickel on freshwater teleosts
- Author:
- Khangarot B.S.
- Year:
- 1 981
- Bibliographic source:
- Acta hydrochim. hydrobiol. Vol. 9 (83): 297-302
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
Test material
- Reference substance name:
- Nickel sulphate
- EC Number:
- 232-104-9
- EC Name:
- Nickel sulphate
- Cas Number:
- 7786-81-4
- IUPAC Name:
- nickel(2+) sulfate
- Details on test material:
- - Name of test material (as cited in study report): Nickelsulfate
- Analytical purity: reagend grade
Constituent 1
Test organisms
- Test organisms (species):
- other: Puntius sophore, Rasbora daniconius neilgeriensis, Channa punctatus and Lebistis reticulatus
- Details on test organisms:
- TEST ORGANISM
- Name: Puntius sophore
- Length at study initiation: 58.25 ± 8.02 mm
- Weight at study initiation: 2.11 ± 0.631 g
- Name: Rasbora daniconius neilgeriensis
- Length at study initiation: 50.19 ± 6.8 mm
- Weight at study initiation: 1.5 ± 0.4 g
- Name: Channa punctatus
- Length at study initiation: 56.7 ± 4.06 mm
- Weight at study initiation: 1.89 ± 0.5 g
- Name: Lebistis reticulatus
- Length at study initiation: 16.21 ± 1.12 mm
- Weight at study initiation: 0.18 ± 0.06 g
ACCLIMATION
- Acclimation period: 15 d
- Type and amount of food: standard fish food
- Feeding frequency: thrice a week
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 260 ppm CaCO3
- Test temperature:
- 17.5 - 21.5 °C
- pH:
- 6.8 - 7.8
- Dissolved oxygen:
- 5.92-8.1 ppm
- Nominal and measured concentrations:
- Nominal test concentrations: 7, 11, 15.5, 28, 37, 42, 56 ppm
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Material: glass aquaria
- Type of flow-through: not stated
- Renewal rate of test solution: every 24 hours
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 3
- No. of vessels per control (replicates): 3
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: according to standard APHA 1971 (Standard methods for the examination of water and wastewater)
- Total organic carbon: 293 ppm
- Alkalinity: 170 ppm (CaCO3)
- Conductivity: 9.8 µS cm-1
- Intervals of water quality measurement: every 24 h
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
symptoms and mortality were observed every 24 hours
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 13.57 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: P. sophore
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 48.83 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Rasbora daniconius neilgeriensis
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 24.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Channa punctatus
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 34.9 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Nickel
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Lebistis reticulatus
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 21.43 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: P. sophore. Result calculated for Nickeldihydroxid
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 77.13 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Rasbora daniconius neilgeriensis. Result calculated for Nickeldihydroxid
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 38.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Channa punctatus. Result calculated for Nickeldihydroxid
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 55.12 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: Nickeldihydroxid
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Lebistis reticulatus. Result calculated for Nickeldihydroxid
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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