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Environmental fate & pathways

Adsorption / desorption

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Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to O.E.C.D. Test Guideline No. 121 with GLP compliance.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
yes
Remarks:
HPLC column temperature was 40 degrees C.
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC estimation method
Media:
soil/sewage sludge

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Type:
Constituent
Details on test material:
As per IUCLID5 Sections 1.1. -1.4.
Radiolabelling:
no

Study design

Test temperature:
40 degrees C

HPLC method

Details on study design: HPLC method:
A sample of BPA-Tars was dissolved in acetonitrile at a concentration of approximately 1.7 mg/mL for loading onto the HPLC column. Calibration substances were dissolved in acetonitrile/deionized water 1:1. An HP 1200 High Performance Liquid Chrromatograph (HPLC) was used for assessment. The operation conditions were: Column type LiChrospher 100 CN, particle diameter 5 um, length 250 mm and inner diameter 5 um. The Mobile phase was deionized water at pH 6 and acetonitrile 1:1 and the Flow rate was 1.5 mL/min. The Injection volume was 2 uL and the ccolumn temperature was 40 degrees C. Detection was by UV at 216 nm.

Batch equilibrium or other method

Computational methods:
The adsorption coefficient was deduced from the capacity factor (k), given by the expression where, tR is the retention time of the test substance, and t0 is the dead-time, i.e. the average time a solvent molecule needs to pass the HPLC column. Linear-regression was employeed form data extrapolation.

Results and discussion

Adsorption coefficient
Type:
log Koc
Value:
2.8
Temp.:
40 °C
Remarks on result:
other: Based on area - % weighted for all nine BPA-Tars HPLC peaks.

Results: HPLC method

Details on results (HPLC method):
Retention Time Area % Log Koc
_______________________________________________
2.31 1.726 1.57
3.03 39.16 2.36
3.50 17.24 2.73
3.81 16.39 2.93
4.51 17.15 3.30
4.86 2.343 3.46
5.725 2.945 3.80
6.15 1.693 3.94
8.345 1.358 4.52
_____________________________________________

Results: Batch equilibrium or other method

Statistics:
No data

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Based on area - % weighted Log Koc for all HPLC peaks of the test substance 2-Acetone polymer with phenol (BPA-Tars) the calculated Log Koc is 2.8. This finding suggests that BPA-Tars will have low mobility in soil. However, this Log Koc value indicates that BPA-Tars is expected to adsorb to suspended solids and sediment if released to the aquatic environment.
Executive summary:

2 -Acetone polymer with phenol (BPA-Tars) was assessed by an O.E.C.D. Testing Guideline No. 121 HPLC method to derive a Absorption/Desorption coeficient (Koc). Based on area - % weighted Log Koc for all HPLC peaks of the test substance BPA-Tars, the calculated Log Koc is 2.8. This finding suggests that BPA-Tars will have low mobility in soil. However, this Log Koc value indicates that BPA-Tars is expected to adsorb to suspended solids and sediment if released to the aquatic environment.