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Toxicity to aquatic invertebrates:

The results from a GLP study for short-term toxicity to daphniae reveal that L-phenylalanine does not show aquatic toxicity.

The test results for acute toxicity of L-phenylalanine to daphnia were:

The 48-hour NOEC was determined to be 100 mg test item/L. The 48-hour LOEC was determined to be > 100 mg test item/L and the 48-hour EC50 value was determined to be > 100 mg test item/L.

Toxicity to algae:

The toxic effect of the test item L-phenylalanine to Algae was assessed in a GLP guideline growth inhibition study. In this study L-Phenylalanine was found not to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 hours. A slight stimulation on the growth rate and a significant stimulation on the yield were observed.

The NOEC-value of the test item for both inhibition of growth rate and inhibition of yield after 72 hours was 100 mg/L. The EC50-values of the test item for both inhibition of growth rate (ErC50) and yield (EyC50) after 72 hours were > 100 mg/L.

The results do not trigger classification.