Registration Dossier

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Readily biodegradable: 88.4% (ThOD) in 28 days (OECD 301 F)

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

No studies investigating the biodegradability of sodium ethylparaben (CAS No. 35285 -68 -8) are available. Therefore, biodegradation data of the corresponding acid ethylparaben (CAS No. 120 -47 -8) are used as read across.

This read across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach as is explained within the analogue justification in section 13. Except for different cations (hydrogen vs. sodium) the anions of both the source and target substance have identical chemical structures. Since dissociation of the sodium salt under environmental conditions (pH 4 - 9) yields the same ionic species as the acidic form of the substance, this read across can be considered as justified.

For the analogue read across substance ethylparaben, biodegradation data from studies are available.

Data on the biodegradability of ethylparaben are presented in the dossier “Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products” by the Danish Ministry of Environment and Energy. Herein, results from a study according to OECD guideline 301 F are cited. In this test, 20 mg/L ethylparaben were incubated for 28 days and a valid reference control was included. Based on the theoretical oxygen demand, ethylparaben attained 88.4% degradation in 28 days and can therefore be classified as readily biodegradable according to OECD criteria. Additionally data on anaerob degradation were presented in the dossier. The results show that the test item is not anaerob biodegradable.