Registration Dossier
Registration Dossier
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EC number: 432-820-3 | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in accordance with generally accepted scientific principles, possibly with incomplete reporting or methodological deficiencies, which do not affect the quality of relevant results
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Details on test material:
- - Name of test material (as cited in study report): S178207
- Physical state: White solid
- Analytical purity: 91.4% total ligand
- Lot/batch No.: NBZ 0155/44
- Stability under test conditions: Stable
- Storage condition of test material: In the dark at ambient temperature.
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 14 mg/L
- Temp.:
- 25 °C
- pH:
- > 6.64 - < 7.34
- Details on results:
- Result: 14 mg/l at 25°C ± 1°C
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
Mean result = 14 mg/l at 25°C ± 1°C - Executive summary:
Water solubility determined by the shaking flask method using distilled water. (EU Method A6). The test substance was added to distilled water at an elevated temperature (30C +/- 1°C). When saturation was achieved, the mixture was equilibrated at 25°C and the concentration of the test substance determined in the aqueous solution.
Guidelines state that results with a repeatability of 15% are deemed constant. Repeatability is greater than this but due to the low level of test substance in solution, it is felt that the results are acceptable.
Mean result = 14 mg/l at 25°C ± 1°C
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