Registration Dossier
Registration Dossier
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EC number: 231-165-9 | CAS number: 7440-57-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The conduct of acute toxicity studies by either the oral, inhalation or dermal routes of administration was waived based on the unlikely exposure to gold metal via these routes. Bio-elution tests using artificial gastric fluid and artificial sweat showed no metal release above the limit of detection (1 µg/L). In addition, the granulometry of gold powder showed that less than 10 % of the substance passed through a 100 µm sieve hence it was considered unlikely to be significantly inhalable.
Justification for classification or non-classification
Through the conduct of bio-elution tests in artificial gastric fluid and sweat and the assessment of particle size, it was concluded that no meaningful studies could be conducted and that gold metal was not classifiable for this endpoint.
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