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Long-term toxicity to fish

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Endpoint:
long-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
freshwater
Total exposure duration:
32 d
Duration:
32 d
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
6.771 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Esters: Maximum LogKow: 8.0 (ChV)
Conclusions:
Estimated Chronic Value : 6.7 mg/L
Intermediate substance is not estimated to be toxic to fishes.
Endpoint:
long-term toxicity to fish, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
saltwater
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
14.713 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Esters: Maximum LogKow: 8.0 (ChV)
Conclusions:
Estimated Chronic Value : 14.7 mg/L
Intermediate substance is not estimated to be toxic to fishes.

Description of key information

Indicated results are "Chronic values" as obtained from ECOSAR 1.11

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
6.7 mg/L

Marine water fish

Marine water fish
Effect concentration:
14.7 mg/L

Additional information

Lowest NOEC could be estimated to around 4.7 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)


Intermediate substance is not estimated to be toxic to fish.