Registration Dossier
Registration Dossier
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EC number: 202-858-3 | CAS number: 100-50-5
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- repeated dose toxicity: other route
- Remarks:
- other: repeated dose toxicity studies
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- Bandman, A., L.; et al.
- Year:
- 1 994
- Bibliographic source:
- Vredny Chimiceskie Galogen, Chima, 394-395
Materials and methods
- Principles of method if other than guideline:
- other: 30 day and 4 months repeated dose toxicity study (application way ?)
Test material
- Reference substance name:
- Cyclohex-3-ene-1-carbaldehyde
- EC Number:
- 202-858-3
- EC Name:
- Cyclohex-3-ene-1-carbaldehyde
- Cas Number:
- 100-50-5
- Molecular formula:
- C7H10O
- IUPAC Name:
- cyclohex-3-ene-1-carbaldehyde
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- unspecified
- Duration of treatment / exposure:
- 4 months
Doses / concentrations
- Remarks:
- Doses / Concentrations:
4 months toxicity study: 5, 22, 53 mg/m3, 30 day toxicity study: 1/5 LD50
- No. of animals per sex per dose:
- no data
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
4 months studies: Clinical signs: effects on the CNS, reduced activity of aldolase and katalase, adverse effects on different organs like brain, liver, kidney, lung
Applicant's summary and conclusion
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