Registration Dossier

Administrative data

Endpoint:
repeated dose toxicity: other route
Remarks:
other: repeated dose toxicity studies
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Bandman, A., L.; et al.
Year:
1994
Bibliographic source:
Vredny Chimiceskie Galogen, Chima, 394-395

Materials and methods

Principles of method if other than guideline:
other: 30 day and 4 months repeated dose toxicity study (application way ?)

Test material

Constituent 1
Chemical structure
Reference substance name:
Cyclohex-3-ene-1-carbaldehyde
EC Number:
202-858-3
EC Name:
Cyclohex-3-ene-1-carbaldehyde
Cas Number:
100-50-5
Molecular formula:
C7H10O
IUPAC Name:
cyclohex-3-ene-1-carbaldehyde

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
unspecified
Duration of treatment / exposure:
4 months
Doses / concentrations
Remarks:
Doses / Concentrations:
4 months toxicity study: 5, 22, 53 mg/m3, 30 day toxicity study: 1/5 LD50
No. of animals per sex per dose:
no data

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

4 months studies: Clinical signs: effects on the CNS, reduced activity of aldolase and katalase, adverse effects on different organs like brain, liver, kidney, lung

Applicant's summary and conclusion