Registration Dossier
Registration Dossier
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EC number: 201-377-6 | CAS number: 81-81-2
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 990
Materials and methods
- Principles of method if other than guideline:
- Method data are not available as the report details are unpublished.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Warfarin
- EC Number:
- 201-377-6
- EC Name:
- Warfarin
- Cas Number:
- 81-81-2
- Molecular formula:
- C19H16O4
- IUPAC Name:
- 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
Constituent 1
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
Results and discussion
Bioaccumulation factor
- Value:
- <= 21.6 dimensionless
Any other information on results incl. tables
In the depuration phase the warfarin concentration decreased rapidly to levels at or below the detection limit so that after 11 days (the first day of warfarin measurement after termination of exposure) warfarin was no longer detectable in any of the test groups. Valid estimates of DT50 and DT90 can therefore not be provided. In conclusion DT90 ≤11 days.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
