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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
not applicable
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Water solubility:
< 3 µg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 7
Remarks on result:
other: Value given by the study director
Key result
Water solubility:
0.9 µg/L
Conc. based on:
test mat.
Temp.:
20
pH:
ca. 7
Remarks on result:
other: mean value of column 1 and 2
Details on results:
The water solubility of the test item Macrolex Violett 3R trocken determined by the column elution method at 20 °C was < 3 μg/l, it corresponds to < 0.003 mg/l and to < 0.000003 g/l (mean value of both columns).
Additional information of the measured concentrations of column 1:
Fraction 1 = 3.36 μg/l Macrolex Violett 3R trocken Fraction 20 = 10.67 μg/l Macrolex Violett 3R trocken Fraction 21 = 12.62 μg/l Macrolex Violett 3R trocken
The measured values of fraction 2 – 19 vary from not detectable to 1.7 μg/l Macrolex Violett 3R trocken.
Mean value = 0.68 μg/l Macrolex Violett 3R trocken of column 1.
Additional information of the measured concentrations of column 2:
Fraction 1 = 39.97 μg/l Macrolex Violett 3R trocken Fraction 8 = 4.37 μg/l Macrolex Violett 3R trocken
The measured values of fraction 2 – 10 vary from not detectable to 2.46 μg/l Macrolex Violett 3R trocken.
Mean value = 1.08 μg/l Macrolex Violett 3R trocken of column 2.
Mean value of column 1 and column 2: 0.9 µg/L.
Conclusions:
The water solubility of the Solvent Violet 36 determined by the column elution method at 20 °C was < 3 μg/L (mean value of both columns) (pH-value approx. 7).
Executive summary:

The study was performed according to guideline OECD 105 by the column elution method. For the support material approximately 600 mg silica gel Chromosorb W/AW (0.15 -0.18 mm) was transferred to a 100 ml pear-shaped distilling flask. Approximately 11 mg of the test item was weighed into a 100 ml measuring flask. Acetone was added to dissolve the test substance and the flask was filled up to the mark with acetone. 5 ml of this solution was added to the support material and the solvent was completely evaporated using a rotary evaporator. The support material was soaked in demineralized water and the suspension was poured into the water-filled micro column. After equilibrating 10 ml fractions from the micro column were collected and their concentration was determined by HPLC-analysis.

. The water solubility of the Solvent Violet 36 determined by the column elution method at 20 °C was < 3 μg/L (mean value of both columns) (pH-value approx. 7).

Description of key information

The water solubility of the Solvent Violet 36 determined by the column elution method at 20 °C was < 3 μg/L, it corresponds to < 0.003 mg/L and to < 0.000003 g/L (mean value of both columns). Detailed investigation yielded a water solubility of 0.9 µg/L (mean value of 2 columns).

Key value for chemical safety assessment

Water solubility:
0.9 µg/L
at the temperature of:
20 °C

Additional information