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Physical & Chemical properties

Partition coefficient

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Description of key information

The partition coefficient of test substance 1,3-isobenzofurandione, reaction products with methylquinoline and quinoline(CAS No.8003-22-3)was determined as per the HPLC method (OECD Guideline-117). The Log Pow value was found to be 3.550± 0.001 at 25°C.

Key value for chemical safety assessment

Log Kow (Log Pow):
3.55
at the temperature of:
25 °C

Additional information

The partition Coefficient n-octanol/water of 1,3-isobenzofurandione, reaction products with methylquinoline and quinolone (CAS No. 8003-22-3) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for Testing of Chemicals. The reference substances were chosen according to structural similarity with the test substance. The reference substances were 4 Acetyl pyridine, Acetophenone, Benzophenone, Naphthalene, Biphenyl, N butyl benzene having Pow value ranging from 0.5 to 4.6.

The Log Pow value was found to be 3.550± 0.001 at 25°C.