Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no data: aquatic toxicity unlikely

Marine water

Hazard assessment conclusion:
no data: aquatic toxicity unlikely

STP

Hazard assessment conclusion:
no data: aquatic toxicity unlikely

Sediment (freshwater)

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Sediment (marine water)

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Classification of 1, 3-isobenzofurandione, reaction products with methyl quinoline and quinoline for effects in the environment

In determining the classification appropriate to1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.

Persistence

Reliable studies are available to demonstrate that 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is non-persistent in nature (i.e. water, sediment and soil) and so is considered to be biodegradable in the environment. In other words 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline may therefore be expected to degrade rapidly. Thus it can be inferred that 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is non-persistent.

1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is non-persistent and does not satisfy the criteria for classification as persistent (P). 

 

Bioaccumulation

Thought the estimated log Kow values for 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is greater than 4 (Log Kow = 4.1). The potential for 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 2000. The estimated BCF of 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is highest 61.25 dimensionless and below the threshold of 2000. 

Thus 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline does not satisfy the criterion for classification as bio accumulative (B).

 

Toxicity

The aquatic toxicity profile for the chemical, 1,3-isobenzofurandione, reaction products with methyl quinoline and quinolone cannot be established as the substance is poorly soluble as so long term study will have required for finalization. Further the short term values cannot be considered as valid since no mortality was observed even at a range below the low solubility (a substance will not be present in solution at a concentration above its solubility, unless solubilized by other substances). Thus, as on date the aquatic toxicity is considered as negative considering the BCF criteria of <500 for the chemical.

So, 1,3-isobenzofurandione, reaction products with methyl quinoline and quinolinedoes not satisfy the environmental effects criterion for classification as toxic (T).

Further as per Annex XIII of the REACH regulation it can be inferred that1,3-isobenzofurandione, reaction products with methyl quinoline and quinolineis not a PBT (including vPvB) substance.

Conclusion on classification

Classification is not triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.