Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: limited information available

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
No information
Author:
Hoechst AG
Year:
1986
Bibliographic source:
unpublished data
Reference Type:
secondary source
Title:
IUCLID data set for CAS: 105-45-3
Author:
ECB
Year:
2000
Bibliographic source:
ECB IUCLID

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
ETAD Fermentation Tube Method
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl acetoacetate
EC Number:
203-299-8
EC Name:
Methyl acetoacetate
Cas Number:
105-45-3
Molecular formula:
C5H8O3
IUPAC Name:
methyl 3-oxobutanoate
Details on test material:
- Name of test material (as cited in study report): Methyl acetoacetate

Sampling and analysis

Analytical monitoring:
no

Test organisms

Test organisms (species):
anaerobic bacteria from a domestic water treatment plant

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
24 h

Results and discussion

Effect concentrations
Duration:
24 h
Dose descriptor:
EC0
Effect conc.:
500 - 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: damage threshold

Applicant's summary and conclusion