Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Additional information:

In a guinea pig maximization test (according to OECD Guideline 406, positive control not required by 1981 guideline version), sensitization was not observed in any of 20 animals (Huels AG, 1988a).

Migrated from Short description of key information:
Isophorone is not sensitizing in animal studies.

Justification for classification or non-classification

Based on the results of the sensitisation test, isophorone does not need to be classified according to Directive 67/548/EEC and according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.