Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Conclusion on classification

Classification related key information


Biodegradation in water: 11.2% (DOC removal) in 28 days (OECD 301 E)


Log Kow < -2 (KOWWIN v1.67)


Acute toxicity

- to aquatic invertebrates: EC50 (48 h) = 66 mg/L for Daphnia magna (OECD 202)

- to algae: ErC50 (72 h) > 100 mg/L, for Pseudokirchnerella subcapitata (OECD 201)


Chronic toxicity

- to aquatic invertebrates: not available

- to algae: NOEC (72 h) = 50 mg/L for Pseudokirchnerella subcapitata (OECD 201)


Classification justification according to CLP

Based on the data above, reaction mass of potassium sodium (2R,3R)-2-hydroxy-3-(phosphonatooxy) butanedioate and potassium sodium (2S,3S)-2-hydroxy-3-(phosphonatooxy) butanedioate is not readily biodegradable. Based on QSAR calculations, no bioaccumulation into organisms is expected by the reaction mass. Concerning the acute aquatic toxicity, the most sensitive species was Daphnia magna with an EC50 of 66 mg/L. Valid chronic toxicity data are available only for algae. The NOEC for the algae Pseudokirchnerella subcapitata is 50 mg/L. Based on these data, the respective reaction mass is classified as hazardous to the environment in the category Chronic 3 according to Regulation (EC) No 1272/2008 (CLP) and Regulation (EU) No 286/2011 (6th ATP).