Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Due to the lack of sufficient data regarding sensitization, data for the analogue substance 3,5,5-Trimethyl-2 -cyoclohexen-1-one (CAS No. 78-59-1) were taken into account. This substance was analyzed in a study according to OECD Guideline 406 and was found to be not sensitizing (Huels AG, 1989). Because of the structural similarities it can be assumed, that also for 2,5,6 -Trimethyl-2-cyoclohexen-1-one no sensitizing effects have to be expected.

Migrated from Short description of key information:
- Skin sensitization: no sensitizing to skin (Analogy CAS 78-59-1, OECD 406)

Justification for classification or non-classification

Due to negative results in an OECD Guideline study with 3,5,5-Trimethyl-2 -cyoclohexen-1-one (CAS No. 78-59-1) no sensitizing effects of 2,5,6-Trimethyl-2 -cyoclohexen-1-one can be expected and thus it does not need to be classified.