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Administrative data

Key value for chemical safety assessment

Additional information

In studies performed according to OECD Guidelines 471 and 474, the genotoxicity was evaluated in Ames and micronucleus tests, respectively (BASF AG, 1989, 1993). In both tests 2,5,6-Trimethyl-2-cylohexen-1-one was found to be negative for inducing genotoxic effects in vitro and in vivo.

Short description of key information:
Genetic toxicity
- in vitro: negative (Ames, OECD 471)
- in vivo: negative (MNT, OECD 474)

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Due to results obtained in studies performed according to OECD guidelines, no classification for genotoxicity in vitro and in vivo is required.