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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

In vitro studies were GLP-compliant and of high quality (Klimisch 1). Therefore, there is no reason to believe that these results would not be applicable to humans.

Justification for selection of genetic toxicity endpoint

No study is selected , since all three in vitro tests are negative.

Short description of key information:

For 3-Methylpyrazole three in vitro test for genetic toxicity are available:

1. Ames-test: negative result

2. In vitro chromosome abberration test: negative result

3. HPRT-test for point mutations: negative results

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

3 -Methylpyrazole has not to be classified as mutagenic substance.