Sodium 4-(2-methylprop-2-en-1-yl)benzenesulphonate

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: peer reviewed journal

Justification for type of information:

Data is from peer reviewed journal

Qualifier:

according to guideline

Guideline:

other: as mentioned below

Principles of method if other than guideline:

The for shor term toxicity of test was performed as

GLP compliance:

not specified

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

Daphnia magna

Details on test organisms:

TEST ORGANISM
- Common name: Daphnia magna
- Source: cultures maintained in well water at the Monsanto environmental laboratory
- Age at study initiation (mean and range, SD): less than 24h old

Test type:

static

Water media type:

freshwater

Total exposure duration:

48 h

Nominal and measured concentrations:

5 concentrations used

Details on test conditions:

TEST SYSTEM
Test vessel: beaker
- No. of organisms per vessel: Ten daphnids per beaker
- No. of vessels per concentration (replicates): three replicates per concentration.

Key result

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

23 000 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Basis for effect:

mortality

Remarks on result:

other: concentration range from 21340-24830mg/L

Validity criteria fulfilled:

not specified

Conclusions:

48-h static acute toxicity test with Daphnia magna indicated that test material is practically non toxic to this species. The 48-h LC50 was determined to be 23,000 (21,340-24,830) mg/l. No effects were observed below 14,800 mg/l.

Executive summary:

Daphnia magna (<24h old) were exposed to test material for 48h using five concentrations and a control. Ten daphnids per beaker were used with three replicates per concentration. Each beaker contained 200 ml of well water. Test solutions were not aerated and no solvents were used. Dissolved oxygen, pH, alkalinity, hardness and temperature were measured at the beginning and end of the study. 48-h static acute toxicity test with Daphnia magna indicated that test material is practically non toxic to the daphnia magna and the 48-h LC50 was determined to be 23,000 (21,340-24,830) mg/L. No effects were also observed below 14,800 mg/l. Based on the above effect concentration it can be concluded that test material can not be classified as per CLP criteria.

Description of key information

Short term toxicity to aquatic invertebrate:

Daphnia magna (<24h old) were exposed to test material for 48h using five concentrations and a control. Ten daphnids per beaker were used with three replicates per concentration. Each beaker contained 200 ml of well water. Test solutions were not aerated and no solvents were used. Dissolved oxygen, pH, alkalinity, hardness and temperature were measured at the beginning and end of the study. 48-h static acute toxicity test with Daphnia magna indicated that test material is practically non toxic to the daphnia magna and the 48-h LC50 was determined to be 23,000 (21,340-24,830) mg/L. No effects were also observed below 14,800 mg/l. Based on the above effect concentration it can be concluded that test material can not be classified as per CLP criteria.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

14 800 mg/L

Additional information

Short term toxicity to aquatic invertebrate:

Daphnia magna (<24h old) were exposed to test material for 48h using five concentrations and a control. Ten daphnids per beaker were used with three replicates per concentration. Each beaker contained 200 ml of well water. Test solutions were not aerated and no solvents were used. Dissolved oxygen, pH, alkalinity, hardness and temperature were measured at the beginning and end of the study. 48-h static acute toxicity test with Daphnia magna indicated that test material is practically non toxic to the daphnia magna and the 48-h LC50 was determined to be 23,000 (21,340-24,830) mg/L. No effects were also observed below 14,800 mg/l. Based on the above effect concentration it can be concluded that test material can not be classified as per CLP criteria.

In another study for structurally similar read across substance short term toxicity to aquatic invertebrates was performed in daphnia magna for 48 hrs by the method Directive 84/449/EEC, C.2 "Acute toxicity for Daphnia". Effective concentration was determined. After experiment the EC 50 of test material was determined to be >1000 mg/l. Based on the value, the test material was considered to be non-toxic to aquatic invertebrates and can be considered as not classified as per the CLP regulations.