Registration Dossier
Registration Dossier
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EC number: 203-199-4 | CAS number: 104-40-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from authorative database
Data source
Reference
- Reference Type:
- other: authorative database
- Title:
- Analytical Reference Standards and Supplemental Data: The Pesticides and Industrial Chemicals Repository
- Author:
- United States Environmental Protection Agency
- Year:
- 1 984
- Bibliographic source:
- EPA-600/4·84-082 October 1984
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: as per mentioned below
- Principles of method if other than guideline:
- Acute oral toxicity study of 4-Nonylphenol in rat.
- GLP compliance:
- no
- Test type:
- standard acute method
Test material
- Reference substance name:
- p-nonylphenol
- EC Number:
- 203-199-4
- EC Name:
- p-nonylphenol
- Cas Number:
- 104-40-5
- Molecular formula:
- C15H24O
- IUPAC Name:
- 4-nonylphenol
- Details on test material:
- - Name of test material (as cited in study report): p-nonylphenol
- Molecular formula (if other than submission substance): C15-H24-O
- Molecular weight (if other than submission substance): 220.354
- Smiles notation (if other than submission substance): c1(ccc(O)cc1)CCCCCCCCC
- InChl (if other than submission substance): 1S/C15H24O/c1-2-3-4-5-6-7-8-9-14-10-12-15(16)13-11-14/h10-13,16H,2-9H2,1H3
- Substance type: Organic
- Physical state: solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- Not applicable
- Doses:
- 1620 mg/kg
- No. of animals per sex per dose:
- No data available
- Control animals:
- not specified
- Details on study design:
- No data available
- Statistics:
- No data available
Results and discussion
- Preliminary study:
- No data available
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 620 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No data available
- Clinical signs:
- other: No data available
- Gross pathology:
- No data available
- Other findings:
- No data available
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The acute oral LD50 value of 4-Nonylphenol is considered to be 1620mg/kg in rat.
- Executive summary:
The acute oral LD50 value of4-Nonylphenolis considered to be1620mg/kgin rat.
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