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EC number: 203-998-8 | CAS number: 112-70-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from authoritative database
- Qualifier:
- according to guideline
- Guideline:
- other: As mention below
- Principles of method if other than guideline:
- Study was assess to evaluate the nature and effect of test chemical on the growth of algae for the exposure period of 72 hrs.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: Green algae
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 72 h
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.012 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: No data available
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.003 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: Other details not known
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.09 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Biomass and area under the growth curve
- Remarks on result:
- other: Other details not known
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.017 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Biomass and area under the growth curve
- Remarks on result:
- other: Other details not known
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Based on the growth rate inhibition of green algae due to the exposure of tes chemical and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l.
- Executive summary:
Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.
Reference
Description of key information
Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.012 mg/L
- EC10 or NOEC for freshwater algae:
- 0.003 mg/L
Additional information
Based on the various experimental data for the target chemical study have been reviewed to determine the toxic nature on the growth of aquatic algae and cyanobacteria. The studies are as mentioned below:
In the first key study for the target chemical was described in authorative database,
Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.
Similarly in the second supporting study for the target chemical from secondry source says that the chemical was toxic. Study was assess to evaluate the nature and effect of test chemical on the growth of algae for the exposure period of 72 hrs. After the exposure of chemical for 72 hrs, the EC50 was determine to be 0.1-1 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.
The fourth study consider for the test chemical from authorative database. Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.56 mg/l and 0.028 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.72 mg/l and 0.09 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.
Based on the experimental data for the test chemical it can be concluded that the substance is considered to be toxic to aquatic algae and cyanobacteria and classified as aquatic acute 1 category as per the CLP classification criteria.
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