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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

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Description of key information

The concentrations of test item causing a 50 % and 10% reduction in growth rate were estimated:
72h-EC50 = 1.4 mg/L (95% CI: 0.87 - 2.1 mg/L)
72h-EC10 = 0.38 mg/L (95% CI: 0.17 - 0.63 mg/L)

Key value for chemical safety assessment

EC50 for freshwater algae:
1.4 mg/L
EC10 or NOEC for freshwater algae:
0.38 mg/L

Additional information

The determination of the growth inhibition of the freshwater algae Pseudokirchneriella subcapitata exposed to the test item for 72 hours was assessed according to the OECD 201 guideline.

Algae were exposed from 0.2 to 9.4 mg/L of test item dissolved in dilution water. The toxic effect measured during the assay was the inhibition of cellular multiplication over a time period of 72 hours.

The concentrations of test item causing a 50% and a 10% reduction in biomass and in growth rate were estimated. The results were as follows:

Growth rate – Cell multiplication: 72h-EC50 = 1,4 mg/L (95% CI: 0.87 - 2.1 mg/L); 72h-EC10 = 0.38 mg/L (95% CI: 0.17 - 0.63 mg/L)

Cell growth – Biomass: 72h-EC50 = 0.46 mg/L (95% CI: 0.26 - 0.69 mg/L); 72h-EC10 = 0.11 mg/L (CI 95%: 0.038 - 0.2 mg/L)