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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Physical & Chemical properties


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Description of key information

Isobutyl-R-lactate is considered to be non-explosive, based on screening-level assessment.

Key value for chemical safety assessment

non explosive

Additional information

According to Regulation (EC) No 1272/2008 (CLP Regulation) and ECHA's CLP guidance, explosive properties are associated with the presence of certain chemical groups in a molecule which can react to produce very rapid increases in temperature and/or pressure. Examples of such chemical groups are:

  • C-C unsaturation (e.g. acetylenes, acetylides, 1, 2-dienes);
  • C-Metal, N-Metal (e.g. Grignard reagents, organo-lithium compounds);
  • Contiguous nitrogen atoms (e.g. azides, aliphatic azo compounds, diazonium salts, hydrazines, sulphonylhydrazides);
  • Contiguous oxygen atoms (e.g. peroxides, ozonides);
  • N-O (e.g. hydroxyl amines, nitrates, nitro compounds, nitroso compounds, N-oxides, 1,2-oxazoles);
  • N-halogen (e.g. chloramines, fluoroamines);
  • O-halogen (e.g. chlorates, perchlorates, iodosyl compounds).

Isobutyl-R-lactate does not contain any of these chemical groups. Although it is acknowledged that the above list is not exhaustive the molecular structure of the substance nevertheless clearly suggests that explosive hazards are absent. Furthermore, the oxygen balance of the molecule is –197, which is only marginally higher than the trigger value of –200, which allows classification of a substance as non-explosive even if chemical groups associated with explosive hazards are present. Based on this screening level assessment, testing of explosive properties of isobutyl-R-lactate is considered to be scientifically unjustified. Isobutyl-R-lactate is therefore not classified as an explosive substance.

Justification for classification or non-classification

Isobutyl-R-lactate does not contain any chemical groups that are associated with an explosive hazard. Furthermore, the oxygen balance of the molecule is clearly negative, with a value of –197. Isobutyl-R-lactate is therefore not classified as an explosive substance.