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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

The log Pow of isobutyl-(S)-lactate is 1.1. QSAR estimation revealed a log Pow value of 0.73 for isobutyl-(R)-lactate.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

According to Clary, Feron & van Velthuijsen (1998) the log Pow of isobutyl-(S)-lactate is 1.1. The value can be extrapolated to the target substance isobutyl-(R)-lactate without restrictions, since being the optical antipode. The octanol-water partition coefficient of isobutyl-(R)-lactate was also estimated by QSAR calculation using EPISuite 4.1/KOWWIN v.1.68. The estimated log Pow of 0.73 is relatively low and suggests hydrophilic properties associated with a decreased potential for adsorption and bioaccumulation. The value is in good agreement with that determined by Clary et al. (1998) for isobutyl-(S)-lactate. The QSAR estimate was selected as the key value since Clary et al. (1998) is only scarcely documented.