Registration Dossier
Registration Dossier
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EC number: 408-200-3 | CAS number: 63187-91-7 FRESCOLAT MGA
Endpoint summary
Administrative data
Description of key information
Additional information
Valid acute toxicity tests with the test substance are available for three freshwater species from three trophic levels. The studies show that fish are the most sensitive species.
Toxicity to fish:
The short-term toxicity to fish is assessed in carp based on a semi-static test according to OECD 203 over 96h.
The resulting 96h LC50 for freshwater fish is 24 mg/L.
Toxicity to aquatic invertebrates:
The short-term toxicity to dapnia is assessed based on a semi-static test according to OECD 202 over 48h.
The resulting 48h EC50 for freshwater invertebrates is 63.7 mg/L.
Toxicity to aquatic algae:
One study is available in which the toxicity to aquatic algae is assessed based on a static test according to OECD 201 over 72h.
The resulting 72h EC50 for freshwater algae is 80.1 mg/L. The 72h EC10 is determined to be 31.4 mg/L. The NOEC is determined to be 20.0 mg/L.
Toxicity to microorganisms:
One study is available in which the toxicity to microorganisms is assessed based on a Respiration Inhibition test with activated sludge according to OECD 209.
The resulting 3h EC50 is determined to be 629 mg/L. The 3h EC10 is 114 mg/L. The NOEC is 32 mg/L.
In conclusion, based on the available information, it can be assumed that fish are the most sensitive species and therefore an LC50 of 24 mg/L is used in the hazard assessment and for derivation of aquatic PNECs.
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