Registration Dossier
Registration Dossier
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EC number: 205-371-4 | CAS number: 139-66-2
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
In vivo administration of Diphenyl sulphide (DPS) in Male Wistar rats resulted in metabolism via S-oxidation to their corresponding sulphones, via a sulphoxide. These metabolites are eliminated through the urine. It appears that other modes of excretion may contribute to the overall elimination of these sulphides like lung and biliary excretion. Thus, it can be concluded that the chemical diphenyl sulphide (DPS) is not likely to bioaccumulate inside the living organisms and shall exhibit low bio-accumulation potential.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
In vivo administration of Diphenyl sulphide (DPS) in Male Wistar rats resulted in metabolism via S-oxidationto their correspondingsulphones, via a sulphoxide.These metabolites are eliminated through the urine.It appears that other modes of excretion may contribute to the overall elimination of these sulphides like lung and biliary excretion. Thus, it can be concluded that the chemical diphenyl sulphide (DPS) is not likely to bioaccumulate inside the living organisms and shall exhibit low bio-accumulation potential.
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