Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-862-8 | CAS number: 111-36-4
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: unsuitable test system
Data source
Reference
- Reference Type:
- publication
- Title:
- The toxicity of benomyl and some related 2-substituted benzimidazoles to the earthworm Lumbricus terrestris.
- Author:
- Stringer A, Wright MA
- Year:
- 1 976
- Bibliographic source:
- Pestic. Sci. 7, 459-464.
Materials and methods
- Principles of method if other than guideline:
- Method: other: Inhibition of cholinesterase activity
- GLP compliance:
- no
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- IUCLID4 Test substance: other TS: Butyl isocyanate, no purity specified, but freshly distilled
Test organisms
- Test organisms (species):
- other: Lumbricus terrestris
Results and discussion
Effect concentrations
- Duration:
- 75 min
- Dose descriptor:
- EC50
- Effect conc.:
- 3 other: mg/l
- Basis for effect:
- other: Inhibition of enzyme activity
Any other information on results incl. tables
RS-Freetext:
n-Butyl isocyanate inhibited in vitro cholinesterase activity with an IC50 of approximately 3 +/- 0.1 mg/l (30.3 +/- 1.06 µM)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
