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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: unsuitable test system

Data source

Reference
Reference Type:
publication
Title:
The toxicity of benomyl and some related 2-substituted benzimidazoles to the earthworm Lumbricus terrestris.
Author:
Stringer A, Wright MA
Year:
1976
Bibliographic source:
Pestic. Sci. 7, 459-464.

Materials and methods

Principles of method if other than guideline:
Method: other: Inhibition of cholinesterase activity
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
IUCLID4 Test substance: other TS: Butyl isocyanate, no purity specified, but freshly distilled

Test organisms

Test organisms (species):
other: Lumbricus terrestris

Results and discussion

Effect concentrations
Duration:
75 min
Dose descriptor:
EC50
Effect conc.:
3 other: mg/l
Basis for effect:
other: Inhibition of enzyme activity

Any other information on results incl. tables

RS-Freetext:
n-Butyl isocyanate inhibited in vitro cholinesterase activity with an  IC50 of approximately 3 +/- 0.1 mg/l (30.3 +/- 1.06 µM)

Applicant's summary and conclusion

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