Butyl isocyanate

Toxicity to terrestrial plants

Administrative data

Endpoint:

toxicity to terrestrial plants

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study meets generally accepted scientific principles

Data source

Reference

Reference Type:

publication

Title:

N,N'-dibutylurea from n-butyl isocyanate, a degradation product of benomyl. 1. Formation in benlate formulations and on plants. J

Author:

Moye HA, Shilling DG, Aldrich HC, Gander JE, Buszko M, Toth JP, Brey WS, Bechtel B, Tolson JK (1994).

Year:

1994

Bibliographic source:

Agric. Food Chem. 42, 1204-1208.

Materials and methods

Principles of method if other than guideline:

Method: other: Phytotoxicity test method developed by the authors (Moye et al., 1994)

GLP compliance:

no

Test material

Reference

Name:

Unnamed

Type:

Constituent

Details on test material:

IUCLID4 Test substance: other TS: n-Butyl isocyanate, purity > 99 %

Test organisms

Species:

other: other terrestrial plant: fern (Nephrolepis exaltata) and cucumber (Cucumis sativus L.)

Results and discussion

Any other information on results incl. tables

RS-Freetext:
After 24 h both sets of plants showed phytotoxic symptoms.
Dibutylurea was detected in extracts of all treated plants.
Whether the plant phytotoxicity was due to n-butyl
isocyanate or its hydrolysis products dibutylurea or
butylamine was not analyzed. 
The following observations were made:
FERN: 
- After 24 h the ferns showed brown spots on the leaves 
- After 72 h they were totally brown and died off 
CUCUMBER: 
- After 24 h spotted browning of the cotyledons followed by
a browning of the guttation water 
- By 72 h browning to the mature leaves had increased but
had not covered the entire leaves 
- After 72 h the mature leaves exhibited intravenal
yellowing and a yellowing around the edges