Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
other: no data
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
US Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals
Year:
1994
Bibliographic source:
cited in: RTECS April, 1994

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
IUCLID4 Test substance: other TS: n-butyl isocyanate, no data on purity

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Details on exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Statistics:
no data

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 mg/kg bw
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data
Other findings:
no data

Applicant's summary and conclusion