Registration Dossier
Registration Dossier
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EC number: 209-963-3 | CAS number: 599-04-2
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data given, however no information was given on the purity of the test substance.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: ISO/DIS 8192 Part B
- GLP compliance:
- no
Test material
- Reference substance name:
- α-hydroxy-β,β-dimethyl-γ-butyrolactone
- EC Number:
- 209-963-3
- EC Name:
- α-hydroxy-β,β-dimethyl-γ-butyrolactone
- Cas Number:
- 599-04-2
- Molecular formula:
- C6H10O3
- IUPAC Name:
- (3R)-dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
- Details on test material:
- - Name of test material (as cited in study report): 4,4-Dimethyl-3-hydroxy-2H-furanon
Purity: no data
Water solubility: good
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- Municipal activated sludge from laboratory wastewater treatment plant fed with municipal sewage. Concentration of dry substance = 1 g/l.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 30 min
Results and discussion
Effect concentrations
- Duration:
- 30 min
- Dose descriptor:
- other: EC20
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
