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Environmental fate & pathways

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Biodegradation in water: screening tests

In the key GLP study, conducted according to OECD Guideline 301B and EU Method C.4-C, the ready biodegradability of the test material was examined over a 28-day period by measuring CO₂ evolution during exposure to an inoculum of domestic activated sludge under aerobic conditions.

The extent of biodegradation of the test material under the conditions of the study was about 10 %. The test material is not readily biodegradable over a 28-day period in this test since the pass level of 60 % ThCO₂ was not reached.

In the supporting GLP study conducted according to OECD Guideline 301B and EU Method C.4-C, the ready biodegradability of the test material was examined over a 28-day period by measuring CO₂ evolution during exposure to an inoculum derived from activated sludge under aerobic conditions.

The extent of biodegradation of the test material under the conditions of the study was 0 % (mean of duplicate test suspensions) over 28 days. Under the conditions of the test, the test material was not readily biodegradable.