Registration Dossier
Registration Dossier
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EC number: 202-885-0 | CAS number: 100-74-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 1.2 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 12 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.12 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 60 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 96.4 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 9.6 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 18.6 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
The environmental classification of NEM is currently not harmonized according to the CLP Regulation (EC) 1272/2008 and the Dangerous Substance Directive 67/548/EC.
Based on available acute toxicity data for 4-ethylmorpholine, the lowest valid effect concentration for freshwater aquatic organisms is > 100 mg/L. Two reliable chronic datapoints are available for 4-ethylmorpholine, a 21-d NOEC daphnia of 100 mg/L and a 96-h ErC10 algae of 61.2 mg/L which are used for the PNEC derivation. Based on these results and although the test substance is not readily biodegradable, it should not be classified for Acute or Chronic toxicity for the aquatic environment according to Annex 1 (section 4.1.2.6) of the CLP Regulation. Based on the same criteria the substance should not be classified for the environment under the Dangerous Substance Directive 67/548/EC (see Annex VI section 5.2.1.2).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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