Registration Dossier
Registration Dossier
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EC number: 239-362-1 | CAS number: 15332-99-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Long-term toxicity to invertebrates: 21 d NOEC 28.1 mg/l (OECD 211 Daphnia magna reproduction test), read-across from an analogous substance,trimethoxy(vinyl)silane (CAS 2768-02-7 ). The NOEC is equivalent to 20.1 mg/l expressed in terms of vinylsilanentriol.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 20.1 mg/L
Additional information
There are no reliable long-term invertebrate toxicity data available for tris(isopropenyloxy)(vinyl)silane (CAS 15332-99-7), therefore good quality data for an appropriate structural analogue, trimethoxy(vinyl)silane (CAS 2768-02-7), have been read across. Both substances share the same silanol hydrolysis product, vinylsilanetriol. The other hydrolysis products are propen-2-ol/acetone and methanol, respectively.
A 21 d NOEC of 28.1 mg/l has been determined for the effects of trimethoxy(vinyl)silane (CAS 2768-02-7) on reproduction of Daphnia magna. In view of the exposure regime it is likely that the test organisms were exposed predominantly to the hydrolysis products of the tested substance. The results may be expressed in terms of concentration of the hydrolysis product, vinylsilanetriol, by applying a molecular weight correction: (MW of silanol=106.15 / MW of parent=148.24) * 28.1 = 20.1 mg/l as vinylsilanetriol.
Refer to the discussion in the Section 6 endpoint summary for further discussion of the approach to chemical safety assessment for this registration substance, and justification for read-across used.
References:
Ministry of the Environment, Government of Japan (2006a). Daphnia magna, reproduction test by silane, ethenyltrimethoxy-. Mitsubishi Chemical Safety Institute Ltd., Yokohama Laboratory, Yokohama, Japan. Study reference number A050113. Study owner Ministry of the Environment, Government of Japan. Report date 2006-05-24.
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