Registration Dossier

Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption: screening
Type of information:
other: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Remarks:
The complete read across justification is detailed in section 13. Test substance is an isomer of the substance under registration; structural difference is not expected to significantly impact adsorption/desorption. Source study has reliability 2: only limited information available from a migrated NONS file, as per Article 25(3) request.
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
GLP compliance:
yes
Type of method:
HPLC estimation method
Media:
soil
Type:
Koc
Value:
< 1.45

The substance was not retained on the column. The log Koc was estimated to be < -3 by extrapolation.

Validity criteria fulfilled:
not specified
Conclusions:
Koc < 1.45
logKoc < -3
Executive summary:

Method

The test has been conducted according to the OECD guideline 121. Information was derived from migrated NONS file, as per Article 25(3) request, with permission to refer granted by ECHA.

 

Results

Koc < 1.45

logKoc < -3.

Description of key information

Koc < 1.45 
logKoc < -3.

Key value for chemical safety assessment

Koc at 20 °C:
1.45

Additional information

[LogKoc: -3.0]