Registration Dossier
Registration Dossier
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EC number: 277-955-7 | CAS number: 74664-50-9
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The complete read across justification is detailed in section 13. Test substance is an isomer of the substance under registration; structural difference is not expected to significantly impact the acute toxicity potential. Source study has reliability 2: only limited information available from a migrated NONS file, as per Article 25(3) request.
Data source
Reference
- Reference Type:
- other: information from migrated NONS file, as per Article 25(3) request, permission to refer granted by ECHA
- Title:
- Unnamed
- Year:
- 1 985
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- Principles of method if other than guideline:
- No information on the method is available
- GLP compliance:
- yes
Test material
- Reference substance name:
- Similar substance 01
- IUPAC Name:
- Similar substance 01
- Test material form:
- solid
Constituent 1
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- not specified
- Clinical signs:
- other:
Any other information on results incl. tables
Route of administration: percutaneous.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified according to the CLP Regulation (EC 1272/2008)
- Conclusions:
- LD50 > 2000 mg/kg bw.
- Executive summary:
Method
Test conducted according to OECD guideline 402. No details on method are available. Information from migrated NONS file, as per Article 25(3) request; permission to refer is granted by ECHA.
Results
LD50 > 2000 mg/kg bw.
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