Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation
Remarks:
no data
Type of information:
other: Based on another study
Adequacy of study:
weight of evidence
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: expert judgement

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: GHS Figure 3.3.1. Step 1c - Testing and evaluation strategy for serious eye demage and eye irritation
Principles of method if other than guideline:
The conclusion is based on the result of positive skin irritation result with EPISKIN model.

Test material

Constituent 1
Chemical structure
Reference substance name:
/-/-1α-Ethyl-1,2,3,4,6,7,12,12b α-octahydro-indolo[2,3-a]-quinolizine-1β-yl-ethyl-pyruvate oxime
EC Number:
617-734-8
Cas Number:
85647-38-7
Molecular formula:
C22H29N3O3
IUPAC Name:
/-/-1α-Ethyl-1,2,3,4,6,7,12,12b α-octahydro-indolo[2,3-a]-quinolizine-1β-yl-ethyl-pyruvate oxime

Results and discussion

In vivo

Results
Remarks on result:
other: not relevant

Applicant's summary and conclusion