Registration Dossier
Registration Dossier
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EC number: 943-535-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
The test item is a complex UVCB for which Log Kow was determined using the HPLC method (OECD 117 and EU Method A.8) with a weighted value being reported as 4.65. However, the mean Log Kow for two out of three samples was less than 4.5 indicating that uptake of the organic components of the test item is unlikely and that the aquatic BCF will be below the 2000 L/kg threshold where bioaccumulation becomes a concern (see ECHA Guidance on Information requirements and chemical safety assessment Chapter R11: PBT assessment (Version 2.0; November 2014). Further evidence for low bioaccumulation potential is provided by the most abundant UVCB component (25 %) where EPISUITE BCFBAF v3.01predicts BCF as 3.16 L/kg wet weight based on SMILES for the component even though Log Kow for the same component is estimated as 4.85. As a result, bioaccumulation of the UVCB test item is not expected to occur as the result of exposure to substance or its constituents and, in accordance with REACH Annex IX, section 9.3.2, column 2, experimental investigation is unnecessary because the substance has a low potential for bioaccumulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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